CELLULAR MICRORNA EXPRESSION PROFILE OF CHICKEN MACROPHAGES INFECTED WITH NEWCASTLE DISEASE VIRUS VACCINE STRAIN LASOTA

Cellular MicroRNA Expression Profile of Chicken Macrophages Infected with Newcastle Disease Virus Vaccine Strain LaSota

Vaccines with live, low-virulence Newcastle disease virus (NDV) strains are still the most accepted prevention and control strategies for combating Newcastle disease (ND), a major viral disease that hampers the Dugouts development of the poultry industry worldwide.However, the mechanism underlying vaccine-mediated innate cell immune responses remai

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Toxic effect of silica nanoparticles on endothelial cells through DNA damage response via Chk1-dependent G2/M checkpoint.

Silica nanoparticles have become promising carriers for drug delivery or gene therapy.Endothelial cells could be directly exposed to silica nanoparticles by intravenous administration.However, the underlying toxic effect mechanisms of silica nanoparticles on endothelial cells are still poorly understood.In order to clarify the cytotoxicity of endot

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Current status and trends in large language modeling research

Over the past two decades, language modeling (LM) has emerged as a primary methodology for language understanding and generation.This technology has become a cornerstone within the field of natural language processing (NLP).At its core, LM is designed to train models to predict the probability of the next word or token, thereby generating natural a

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